Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | In stock | $ 57.00 | |
500 μg | 5 days | $ 231.00 | |
1 mg | 5 days | $ 387.00 |
Biological Information | Human Serum Albumin, His Tag immobilized on CM5 Chip can bind Human FcRn, His Tag with an affinity constant of 0.728 μM as determined in SPR assay. |
Description | Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. |
Species | Human |
Expression System | HEK293 |
Tag | C-His-Avi |
Accession Number | P02768-1 |
Synonyms | Serum albumin, PRO0903, Albumin, PRO1341, ALB, ANALBA, FDAH, PRO0883 |
Construction | Recombinant Human Serum Albumin Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Asp25-Leu609.[Accession |P02768-1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 69.4 kDa. Due to glycosylation, the protein migrates to 69-70 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Serum Albumin Protein, Human, Recombinant (His & Avi) Serum albumin PRO 0903 PRO-1341 PRO0903 Albumin PRO-0903 PRO-0883 PRO1341 ALB ANALBA FDAH PRO 0883 PRO 1341 PRO0883 recombinant recombinant-proteins proteins protein