TIGIT Protein, Human, Recombinant (HEK293, His)

Name: TIGIT Protein, Human, Recombinant (HEK293, His)
Brand: TargetMol
SKU: TMPS-00134
Rating: 4.5 (1 reviews)

(Synonyms: VSIG9, VSTM3, WUCAM, T-cell immunoreceptor with Ig and ITIM domains, T cell immunoreceptor with Ig and ITIM domains) Copy Product Info

Synonyms: VSIG9, VSTM3, WUCAM, T-cell immunoreceptor with Ig and ITIM domains, T cell immunoreceptor with Ig and ITIM domains

Catalog No. TMPS-00134 Copy Product Info

TIGIT Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells+J15. The accession number is Q495A1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$70	7-10 days	7-10 days
10 µg	$112	7-10 days	7-10 days
20 µg	$183	7-10 days	7-10 days
50 µg	$360	7-10 days	7-10 days
100 µg	$498	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,890	7-10 days	7-10 days
1 mg	$3,390	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	This proten can bind with CHO-K1/aAPC/CD155 Clone by FACS analysis.
Description	TIGIT Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells+J15. The accession number is Q495A1.
Species	Human
Expression System	HEK293 Cells+J15
Tag	His
Accession Number	Q495A1
Construction	Met22-Pro141
Protein Purity	> 90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	VSIG9, VSTM3, WUCAM, T-cell immunoreceptor with Ig and ITIM domains, T cell immunoreceptor with Ig and ITIM domains
Research Background	T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an immune receptor present on some T cells and natural killer cells (NK). This protein could bind to CD155 (PVR) with high affinity, which causes increased secretion of IL-10 and decreased secretion of IL-12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. TIGIT could also bind to CD112 (PVRL2) with lower affinity. TIGIT's inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR and the activity is directed through its ITIM domain.

Chemical Properties

Molecular Weight

~16.0 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

You can also refer to dose conversion for different animals. More Dose Conversion

Related Tags: TIGIT Protein, Human, Recombinant (HEK293, His) chemical structure | TIGIT Protein, Human, Recombinant (HEK293, His) molecular weight