Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

TIGIT Protein, Human, Recombinant (HEK293, His)

Catalog No. TMPS-00134

TIGIT Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells+J15. The accession number is Q495A1.

TIGIT Protein, Human, Recombinant (HEK293, His)

TIGIT Protein, Human, Recombinant (HEK293, His)

Catalog No. TMPS-00134
TIGIT Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells+J15. The accession number is Q495A1.
Pack SizePriceAvailabilityQuantity
50 μg $3607-10 days
100 μg $4987-10 days
1 mg $3,3907-10 days
Bulk & Custom
Add to Cart
Questions
View More
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Information

Biological Activity
This proten can bind with CHO-K1/aAPC/CD155 Clone by FACS analysis.
Description
TIGIT Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells+J15. The accession number is Q495A1.
Species
Human
Expression System
HEK293 Cells+J15
TagHis
Accession NumberQ495A1
Synonyms
VSIG9, VSTM3, WUCAM, T-cell immunoreceptor with Ig and ITIM domains, T cell immunoreceptor with Ig and ITIM domains
Construction
Met22-Pro141
Protein Purity
> 90% as determined by SDS-PAGE
Molecular Weight~16.0 kDa (Reducing conditions)
Endotoxin< 1 EU/μg of protein as determined by the LAL method.
FormulationLyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution
Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an immune receptor present on some T cells and natural killer cells (NK). This protein could bind to CD155 (PVR) with high affinity, which causes increased secretion of IL-10 and decreased secretion of IL-12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. TIGIT could also bind to CD112 (PVRL2) with lower affinity. TIGIT's inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR and the activity is directed through its ITIM domain.

Dose Conversion

You can also refer to dose conversion for different animals. More

Sci Citations

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.