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CD74 Protein, Mouse, Recombinant (mFc & His)

Catalog No. TMPJ-00775
Synonyms: HLA class II histocompatibility antigen γ chain, HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, Cluster of Differentiation 74, CD74

Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

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CD74 Protein, Mouse, Recombinant (mFc & His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 110.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,300.00
1 mg 5 days $ 1,980.00
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Biological Description
Technical Params
Product Properties
Description Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
Species Mouse
Expression System Human Cells
Tag C-mFc-6His
Accession Number P04441-2
Synonyms HLA class II histocompatibility antigen γ chain, HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, Cluster of Differentiation 74, CD74
Amino Acid Gln56-Leu215
Construction Recombinant Mouse HLA Class II Histocompatibility Antigen Gamma Chain is produced by our Mammalian expression system and the target gene encoding Gln56-Leu215 is expressed with a mouse IgG1 Fc, 6His tag at the C-terminus.
Protein Purity Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 45-55 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

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Keywords

CD74 Protein, Mouse, Recombinant (mFc & His) HLA class II histocompatibility antigen γ chain HLA-DR antigens-associated invariant chain HLA class II histocompatibility antigen gamma chain Cluster of Differentiation 74 CD 74 CD-74 CD74 recombinant recombinant-proteins proteins protein

 

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