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IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPJ-00284
Synonyms: Interleukin-7 receptor subunit alpha, IL-7R subunit α, IL-7R subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, Il7r, CD127, IL-7R-α, Interleukin-7 receptor subunit α, IL-7RA, IL-7 receptor subunit α

Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.
Species Mouse
Expression System Human Cells
Tag C-Fc
Accession Number P16872
Synonyms Interleukin-7 receptor subunit alpha, IL-7R subunit α, IL-7R subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, Il7r, CD127, IL-7R-α, Interleukin-7 receptor subunit α, IL-7RA, IL-7 receptor subunit α
Amino Acid Glu21-Asp239
Construction Recombinant Mouse Interleukin-7 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Glu21-Asp239 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 61-75 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Sucrose, 3% Glycine, 100mM NaCl, 0.1mM EDTA, 0.05% Tween 80, pH 8.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

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Keywords

IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) Interleukin-7 receptor subunit alpha IL-7R subunit α IL-7R subunit alpha IL-7R-alpha IL-7 receptor subunit alpha Il7r CD127 IL-7R-α Interleukin-7 receptor subunit α IL-7RA IL-7 receptor subunit α CD 127 CD-127 recombinant recombinant-proteins proteins protein

 

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