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IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

(Synonyms: Interleukin-7 receptor subunit α, Interleukin-7 receptor subunit alpha, IL-7R-α, IL-7R-alpha, IL-7RA, IL-7R subunit α, IL-7R subunit alpha, Il7r, IL-7 receptor subunit α, IL-7 receptor subunit alpha, CD127) Copy Product Info

Synonyms: Interleukin-7 receptor subunit α, Interleukin-7 receptor subunit alpha, IL-7R-α, IL-7R-alpha, IL-7RA, IL-7R subunit α, IL-7R subunit alpha, Il7r, IL-7 receptor subunit α, IL-7 receptor subunit alpha, CD127

Catalog No. TMPJ-00284 Copy Product Info
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$727-10 days7-10 days
10 µg$1167-10 days7-10 days
20 µg$1767-10 days7-10 days
50 µg$3107-10 days7-10 days
100 µg$5327-10 days7-10 days
200 µg$9197-10 days7-10 days
500 µg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Loaded Human IL-7-His on HIS1K Biosensor, can bind Mouse IL-7RA-Fc with an affinity constant of 5.91 nM as determined in BLI assay. (Regularly tested)
Description
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.
Species
Mouse
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP16872
Amino AcidGlu21-Asp239
ConstructionGlu21-Asp239
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 10% Sucrose, 3% Glycine, 100 mM NaCl, 0.1 mM EDTA, 0.05% Tween 80, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsInterleukin-7 receptor subunit α, Interleukin-7 receptor subunit alpha, IL-7R-α, IL-7R-alpha, IL-7RA, IL-7R subunit α, IL-7R subunit alpha, Il7r, IL-7 receptor subunit α, IL-7 receptor subunit alpha, CD127
Research Background
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.
Chemical Properties
Molecular Weight61-75 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) chemical structure | IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) molecular weight