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Methylatropine (nitrate)

Name: Methylatropine (nitrate)
Brand: TargetMol
SKU: T36204
Rating: 4.5 (1 reviews)

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Catalog No. T36204Cas No. 52-88-0

Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3

Methylatropine (nitrate)

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Catalog No. T36204Cas No. 52-88-0

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$246	35 days	35 days
25 mg	$668	35 days	35 days
50 mg	$1,180	35 days	35 days
100 mg	$2,170	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	366.414
Formula	C₁₈H₂₆N₂O₆
Cas No.	52-88-0

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 30 mg/mL (81.87 mM), Sonication is recommended.

DMSO: 30 mg/mL (81.87 mM), Sonication is recommended.

DMF: 30 mg/mL (81.87 mM), Sonication is recommended.

PBS (pH 7.2): 10 mg/mL (27.29 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.7292 mL	13.6458 mL	27.2915 mL	136.4577 mL
5 mM	0.5458 mL	2.7292 mL	5.4583 mL	27.2915 mL
10 mM	0.2729 mL	1.3646 mL	2.7292 mL	13.6458 mL
20 mM	0.1365 mL	0.6823 mL	1.3646 mL	6.8229 mL

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
50 mM	0.0546 mL	0.2729 mL	0.5458 mL	2.7292 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc