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Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | TBD | 35 days | |
25 mg | TBD | 35 days | |
50 mg | TBD | 35 days | |
100 mg | TBD | 35 days |
Description | Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3 |
Molecular Weight | 366.414 |
Formula | C18H26N2O6 |
Cas No. | 52-88-0 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 30 mg/mL (81.87 mM), Sonication is recommended. DMSO: 30 mg/mL (81.87 mM), Sonication is recommended. DMF: 30 mg/mL (81.87 mM), Sonication is recommended. PBS (pH 7.2): 10 mg/mL (27.29 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/Ethanol/DMSO/DMF
Ethanol/DMSO/DMF
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