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CD98 Protein, Human, Recombinant (mFc)

(Synonyms: Solute carrier family 3 member 2, SLC3A2, MDU1, Lymphocyte activation antigen 4F2 large subunit, CD98, 4F2hc, 4F2 cell-surface antigen heavy chain) Copy Product Info

Synonyms: Solute carrier family 3 member 2, SLC3A2, MDU1, Lymphocyte activation antigen 4F2 large subunit, CD98, 4F2hc, 4F2 cell-surface antigen heavy chain

Catalog No. TMPJ-00352 Copy Product Info
CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98's role in T cell activation in which the TGF activation could also play a profibrotic role.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$427-10 days7-10 days
10 μg$647-10 days7-10 days
20 μg$987-10 days7-10 days
50 μg$2007-10 days7-10 days
100 μg$3687-10 days7-10 days
200 μg$6857-10 days7-10 days
500 μg$1,5707-10 days7-10 days
1 mg$2,3707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98's role in T cell activation in which the TGF activation could also play a profibrotic role.
Species
Human
Expression System
HEK293 Cells
TagN-mFc
Accession NumberP08195
Amino AcidArg206-Ala630
ConstructionArg206-Ala630
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsSolute carrier family 3 member 2, SLC3A2, MDU1, Lymphocyte activation antigen 4F2 large subunit, CD98, 4F2hc, 4F2 cell-surface antigen heavy chain
Research Background
Chemical Properties
Molecular Weight70-100 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: CD98 Protein, Human, Recombinant (mFc) chemical structure | CD98 Protein, Human, Recombinant (mFc) molecular weight