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Synonyms: Solute carrier family 3 member 2, SLC3A2, MDU1, Lymphocyte activation antigen 4F2 large subunit, CD98, 4F2hc, 4F2 cell-surface antigen heavy chain

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $42 | 7-10 days | 7-10 days | |
| 10 μg | $64 | 7-10 days | 7-10 days | |
| 20 μg | $98 | 7-10 days | 7-10 days | |
| 50 μg | $200 | 7-10 days | 7-10 days | |
| 100 μg | $368 | 7-10 days | 7-10 days | |
| 200 μg | $685 | 7-10 days | 7-10 days | |
| 500 μg | $1,570 | 7-10 days | 7-10 days | |
| 1 mg | $2,370 | 7-10 days | 7-10 days |
| Description | CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98's role in T cell activation in which the TGF activation could also play a profibrotic role. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-mFc |
| Accession Number | P08195 |
| Amino Acid | Arg206-Ala630 |
| Construction | Arg206-Ala630 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Solute carrier family 3 member 2, SLC3A2, MDU1, Lymphocyte activation antigen 4F2 large subunit, CD98, 4F2hc, 4F2 cell-surface antigen heavy chain |
| Research Background |
| Molecular Weight | 70-100 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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