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CD98 Protein, Human, Recombinant (mFc)

Catalog No. TMPJ-00352
Synonyms: Lymphocyte activation antigen 4F2 large subunit, 4F2 cell-surface antigen heavy chain, CD98, MDU1, SLC3A2, 4F2hc, Solute carrier family 3 member 2

CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD98 Protein, Human, Recombinant (mFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 64.00
50 μg 5 days $ 200.00
500 μg 5 days $ 1,570.00
1 mg 5 days $ 2,370.00
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Biological Description
Technical Params
Product Properties
Description CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.
Species Human
Expression System Human Cells
Tag N-mFc
Accession Number P08195
Synonyms Lymphocyte activation antigen 4F2 large subunit, 4F2 cell-surface antigen heavy chain, CD98, MDU1, SLC3A2, 4F2hc, Solute carrier family 3 member 2
Amino Acid Arg206-Ala630
Construction Recombinant Human 4F2 Cell-surface Antigen Heavy Chain is produced by our Mammalian expression system and the target gene encoding Arg206-Ala630 is expressed with a mFc tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 70-100 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Research Background CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.

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Keywords

CD98 Protein, Human, Recombinant (mFc) Lymphocyte activation antigen 4F2 large subunit MDU 1 CD-98 4F2 cell-surface antigen heavy chain CD 98 MDU-1 CD98 MDU1 SLC3A2 4F2hc Solute carrier family 3 member 2 recombinant recombinant-proteins proteins protein

 

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