Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Verdiperstat

🥰Excellent
Catalog No. T5463Cas No. 890655-80-8
Alias AZD3241, AZD 3241

Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.

Verdiperstat

Verdiperstat

🥰Excellent
Purity: 99.36%
Catalog No. T5463Alias AZD3241, AZD 3241Cas No. 890655-80-8
Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$32In StockIn Stock
2 mg$45In StockIn Stock
5 mg$72In StockIn Stock
10 mg$122In StockIn Stock
25 mg$222In StockIn Stock
50 mg$369In StockIn Stock
100 mg$571In StockIn Stock
1 mL x 10 mM (in DMSO)$50In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.36%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
Targets&IC50
Myeloperoxidase:630 nM
In vitro
Verdiperstat (AZD3241) functions as a myeloperoxidase (MPO) inhibitor, demonstrating potency with an IC50 value of 630 nM. It is primarily utilized in the study of neurodegenerative brain disorders[1]. By selectively and irreversibly targeting MPO, Verdiperstat (AZD3241) potentially reduces oxidative stress, consequently diminishing prolonged neuroinflammation.
SynonymsAZD3241, AZD 3241
Chemical Properties
Molecular Weight253.32
FormulaC11H15N3O2S
Cas No.890655-80-8
SmilesCC(C)OCCn1c2cc[nH]c2c(=O)[nH]c1=S
Relative Density.1.34 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 150 mg/mL (592.14 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (15.79 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9476 mL19.7379 mL39.4758 mL197.3788 mL
5 mM0.7895 mL3.9476 mL7.8952 mL39.4758 mL
10 mM0.3948 mL1.9738 mL3.9476 mL19.7379 mL
20 mM0.1974 mL0.9869 mL1.9738 mL9.8689 mL
50 mM0.0790 mL0.3948 mL0.7895 mL3.9476 mL
100 mM0.0395 mL0.1974 mL0.3948 mL1.9738 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

VerdiperstatmyeloperoxidaseInhibitorinhibitGlutathionePeroxidaseGlutathione PeroxidaseAZD-3241
Related Tags: buy Verdiperstat | purchase Verdiperstat | Verdiperstat cost | order Verdiperstat | Verdiperstat chemical structure | Verdiperstat in vitro | Verdiperstat formula | Verdiperstat molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.