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Anti-GPCR RDC1 Antibody (1C445) is a Rabbit antibody targeting GPCR RDC1. Anti-GPCR RDC1 Antibody (1C445) can be used in FCM,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-GPCR RDC1 Antibody (1C445) is a Rabbit antibody targeting GPCR RDC1. Anti-GPCR RDC1 Antibody (1C445) can be used in FCM,WB. |
| Synonyms | RDC-1, RDC1, RDC 1, G-protein coupled receptor RDC1 homolog, G-protein coupled receptor 159, GPRN1, GPR159, GPCR RDC 1, G protein coupled receptor RDC1 homolog, G protein coupled receptor 159, G protein coupled receptor, CXCR7_HUMAN, CXCR-7, CXC-R7, CXCR7, CXCR 7, CXC R7, C-X-C chemokine receptor type 7, CMKOR1, Chemokine orphan receptor 1, Chemokine C X C motif receptor 7, Chemokine (C-X-C motif) receptor 7, C X C chemokine receptor type 7, atypical chemokine receptor 3, ACKR3 |
| Ig Type | IgG |
| Clone | 1C445 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of GPCR RDC1 on PC-3M cells lysates using anti-GPCR RDC1 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of Jurkat cells with GPCR RDC1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:1000-5000; FCM: 1:10-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Members of the C-X-C or α chemokine family are characterized by a pair of cysteine residues separated by a single amino acid and primarily function as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins and include proteins such as IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). C-X-C chemokine receptor type 7 (CXCR-7), also known as RDC-1, is a 362 amino acid receptor for SDF-1. Initially identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor. CXCR-7, with CSCR-4, also acts as a coreceptor for human immunodeficiency viruses (HIV). Highly expressed in monocytes, B-cells and basophils, and highly active in various biological processes, including cell growth, cell adhesion and tumor growth, CXCR-7 may play a role in tumorigenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 41 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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