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ANXA1 Protein, Human, Recombinant (His)

(Synonyms: p35, LPC1, Lipocortin I, Chromobindin-9, Calpactin-2, Calpactin II, ANXA1, ANX1, Annexin-1, Annexin I, Annexin A1) Copy Product Info

Synonyms: p35, LPC1, Lipocortin I, Chromobindin-9, Calpactin-2, Calpactin II, ANXA1, ANX1, Annexin-1, Annexin I, Annexin A1

Catalog No. TMPK-00768 Copy Product Info
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04083.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$46-In Stock
10 μg$72-In Stock
20 μg$115-In Stock
50 μg$2227-10 days7-10 days
100 μg$371-In Stock
200 μg$6737-10 days7-10 days
500 μg$1,4907-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04083.
Species
Human
Expression System
E. coli
TagC-His
Accession NumberP04083
ConstructionMet1-Asn346
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymsp35, LPC1, Lipocortin I, Chromobindin-9, Calpactin-2, Calpactin II, ANXA1, ANX1, Annexin-1, Annexin I, Annexin A1
Research Background
Chemical Properties
Molecular Weight39.5 kDa (predicted) same as Tris-Bis PAGE result.
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: ANXA1 Protein, Human, Recombinant (His) chemical structure | ANXA1 Protein, Human, Recombinant (His) molecular weight