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N-CBZ-Phe-Arg-AMC hydrochloride

🥰Excellent
Catalog No. TP1013LCas No. 70382-26-2
Alias Z-Phe-Arg-Amc HCl, N-CBZ-Phe-Arg-AMC hydrochloride(65147-22-0 Free base)

N-CBZ-Phe-Arg-AMC hydrochloride (Z-Phe-Arg-Amc HCl) is a substrate for catS protease. CatS protease is an important member of the cysteine protease family and is a lysosomal protease. It is expressed in many inflammatory processes and autoimmune diseases and can be used to assess the activity of lysosomal proteases.

N-CBZ-Phe-Arg-AMC hydrochloride
Other Forms of N-CBZ-Phe-Arg-AMC hydrochloride:

N-CBZ-Phe-Arg-AMC hydrochloride

🥰Excellent
Purity: 99.99%
Catalog No. TP1013LAlias Z-Phe-Arg-Amc HCl, N-CBZ-Phe-Arg-AMC hydrochloride(65147-22-0 Free base)Cas No. 70382-26-2
N-CBZ-Phe-Arg-AMC hydrochloride (Z-Phe-Arg-Amc HCl) is a substrate for catS protease. CatS protease is an important member of the cysteine protease family and is a lysosomal protease. It is expressed in many inflammatory processes and autoimmune diseases and can be used to assess the activity of lysosomal proteases.
Pack SizePriceAvailabilityQuantity
2 mg$33In Stock
5 mg$50In Stock
10 mg$70In Stock
25 mg$112In Stock
50 mg$163In Stock
100 mg$239In Stock
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Purity:99.99%
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COA HPLC MS

Product Introduction

Bioactivity
Description
N-CBZ-Phe-Arg-AMC hydrochloride (Z-Phe-Arg-Amc HCl) is a substrate for catS protease. CatS protease is an important member of the cysteine protease family and is a lysosomal protease. It is expressed in many inflammatory processes and autoimmune diseases and can be used to assess the activity of lysosomal proteases.
SynonymsZ-Phe-Arg-Amc HCl, N-CBZ-Phe-Arg-AMC hydrochloride(65147-22-0 Free base)
Chemical Properties
Molecular Weight649.14
FormulaC33H37ClN6O6
Cas No.70382-26-2
SmilesCC=1C=2C(=CC(NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC(OCC4=CC=CC=C4)=O)=O)CCCNC(=N)N)=O)=CC2)OC(=O)C1.Cl
Relative Density.no data available
ColorWhite
AppearanceSolid
SequenceCbz-Phe-Arg-AMC
Sequence ShortFR
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture,keep away from direct sunlight | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (154.05 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5405 mL7.7025 mL15.4050 mL77.0250 mL
5 mM0.3081 mL1.5405 mL3.0810 mL15.4050 mL
10 mM0.1540 mL0.7702 mL1.5405 mL7.7025 mL
20 mM0.0770 mL0.3851 mL0.7702 mL3.8512 mL
50 mM0.0308 mL0.1540 mL0.3081 mL1.5405 mL
100 mM0.0154 mL0.0770 mL0.1540 mL0.7702 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

NCBZPheArgAMChydrochloride(65147220Freebase)
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