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Anti-TGF beta 1 Polyclonal Antibody (Synonyms: transforming growth factor, β1, transforming growth factor, beta...)
Catalog No. TMAB-01827 Copy Product Info
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Anti-TGF beta 1 Polyclonal Antibody is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Polyclonal Antibody can be used in ELISA,WB.
Anti-TGF beta 1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01827
Synonyms transforming growth factor, β1, transforming growth factor, beta 1, TGF β1
Anti-TGF beta 1 Polyclonal Antibody is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Polyclonal Antibody can be used in ELISA,WB.
Anti-TGF beta 1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-TGF beta 1 Polyclonal Antibody is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Polyclonal Antibody can be used in ELISA,WB. |
| Synonyms | transforming growth factor, β1, transforming growth factor, beta 1, TGF β1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with TGF Beta 1 polyclonal antibody, unconjugated (TMAB-01827) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.  |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
| Immunogen | KLH conjugated synthetic peptide: human TGF-Beta 1 |
| Antigen Species | Human |
| Gene Name | TGFB1 |
| Gene ID | |
| Protein Name | Transforming growth factor beta-1 proprotein |
| Uniprot ID | |
| Biology Area | Response to hypoxia,TGF,Angiogenic growth factors,TGF,Co-factors,Hypoxia,tgf beta 1,TGF,Secreted |
| Function | Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. |
| Molecular Weight | Theoretical: 12.8/44 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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