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Anti-XBP1 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-01990
Anti-XBP1 Polyclonal Antibody 2 is a Rabbit antibody targeting XBP1. Anti-XBP1 Polyclonal Antibody 2 can be used in WB.
Anti-XBP1 Polyclonal Antibody 2
Anti-XBP1 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-01990
Anti-XBP1 Polyclonal Antibody 2 is a Rabbit antibody targeting XBP1. Anti-XBP1 Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Polyclonal Application: WB Reactivity: Mouse (predicted:Human,Rat,Pig,Horse,Rabbit,Sheep) |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-XBP1 (TMAB-01990) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29/40 kDa Observed band size: 34 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human XBP1 |
| Antigen Species | Human |
| Gene ID | 7494 |
| Uniprot ID | |
| Biology Area | Transcription Factors,Other factors |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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