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CD155/PVR Protein, Human, Recombinant (aa 21-343, His)

(Synonyms: PVS, PVR, Poliovirus Receptor, Nectin-Like Protein 5, NECL-5, CD155) Copy Product Info

Synonyms: PVS, PVR, Poliovirus Receptor, Nectin-Like Protein 5, NECL-5, CD155

Catalog No. TMPJ-00651 Copy Product Info
Purity: 98.9%
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$5335 days35 days
10 μg$8335 days35 days
20 μg$13235 days35 days
50 μg$25035 days35 days
100 μg$39235 days35 days
200 μg$64635 days35 days
500 μg$1,22035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.9%
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Description
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberA0A0C4DG49
Amino AcidTrp21-Asn343
ConstructionTrp21-Asn343
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
https://cdn.targetmol.com/group3/M00/12/F3/CgoaEGZG00WEUd4dAAAAAL2SIlE513.png
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsPVS, PVR, Poliovirus Receptor, Nectin-Like Protein 5, NECL-5, CD155
Research Background
Chemical Properties
Molecular Weight58 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Store at -80°C

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Keywords

Related Tags: CD155/PVR Protein, Human, Recombinant (aa 21-343, His) chemical structure | CD155/PVR Protein, Human, Recombinant (aa 21-343, His) molecular weight