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Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody (Synonyms: p-Alpha-Synuclein (Y133), p-Alpha-Synuclei...)
Catalog No. TMAC-00292 Copy Product Info
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Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Alpha-Synuclein (Tyr133). Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-00292
Synonyms p-Alpha-Synuclein (Y133), p-Alpha-Synuclein (Tyr133), Alpha-Synuclein (p-Y133), Alpha-Synuclein (p-Tyr133)
Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Alpha-Synuclein (Tyr133). Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-Alpha-Synuclein
(Tyr133) Polyclonal Antibody
(Tyr133) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Alpha-Synuclein (Tyr133). Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody can be used in IF,WB. |
| Synonyms | p-Alpha-Synuclein (Y133), p-Alpha-Synuclein (Tyr133), Alpha-Synuclein (p-Y133), Alpha-Synuclein (p-Tyr133) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from C2C12 cells untreated or treated with Anisomycin using a-Synuclein (Phospho-Tyr133) Antibody TMAC-00292. 2. Immunofluorescence staining of methanol-fixed Hela cells using a-Synuclein (Phospho-Tyr133) Antibody TMAC-00292.   |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95% sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 133 (E-G-Y(p)-Q-D) derived from Human a-Synuclein |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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