Sapropterin free base

Name: Sapropterin free base
Brand: TargetMol
SKU: T21366
Rating: 4.5 (1 reviews)

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Catalog No. T21366Cas No. 62989-33-7

Alias THB, Tetrahydro-6-biopterin, Phenoptin, Dapropterin, BPH4, 6R-BH4

Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatonin, norepinephrine, neurotransmitters 5-HT, it is also a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.

Sapropterin free base

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Catalog No. T21366Alias THB, Tetrahydro-6-biopterin, Phenoptin, Dapropterin, BPH4, 6R-BH4Cas No. 62989-33-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,520	Backorder	Backorder

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Product Introduction

Bioactivity

Description	Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatonin, norepinephrine, neurotransmitters 5-HT, it is also a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.
Synonyms	THB, Tetrahydro-6-biopterin, Phenoptin, Dapropterin, BPH4, 6R-BH4

Chemical Properties

Molecular Weight	241.25
Formula	C₉H₁₅N₅O₃
Cas No.	62989-33-7
Relative Density.	1.89g/cm3

Storage & Solubility Information

Storage	store at low temperature,store under nitrogen \| Powder: -20°C for 3 years \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: Insoluble DMSO: Soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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