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TargetMol | Compound Library

Protease Inhibitor Library

Catalog No. L1100

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of the proteasome, such as bortezomib are now front-line drugs for the treatment of multiple myeloma. Marimastat and batimastat are two of the matrix metalloproteinase inhibitors that can be used to treat cancer. The Protease Inhibitor Library by TargetMol, containing 507 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1100

Protease Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 507 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
  • Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
MMP
Caspase
Proteasome
Virus Protease
Serine Protease
Cysteine Protease
Gamma-secretase
Autophagy
SARS-CoV
Antibacterial
HIV Protease
DPP-4
Endogenous Metabolite
Thrombin
HCV Protease
Bcl-2 Family
NF-κB
PARP
Beta Amyloid
Factor Xa
Anti-infection
TNF
p38 MAPK
Antifungal
Parasite
Reactive Oxygen Species
COX
ERK
Akt
IL Receptor
Cytochromes P450
Carboxypeptidase
Protease
Microtubule Associated
Antibiotic
JNK
PPAR
HSV
Interleukin
DNA/RNA Synthesis
Antiviral
Influenza Virus
Ferroptosis
PI3K
Serine/threonin kinase
Immunology/Inflammation related
P-gp
Dehydrogenase
Antioxidant
TRP/TRPV Channel
Drug Metabolite
ROS
Thrombopoietin Receptor
DUB
PAI-1
HDAC
Amino Acids and Derivatives
Estrogen/progestogen Receptor
PKC
CDK
JAK
Lipoxygenase
Prostaglandin Receptor
Nrf2
Pyroptosis
STAT
5-HT Receptor
GABA Receptor
AChR
Tyrosinase
HIF/HIF Prolyl-Hydroxylase
NO Synthase
BACE
Histamine Receptor
Mitophagy
GSK-3
Wnt/beta-catenin
Rho
Calcium Channel
IAP
Annexin A
Antifection
Fatty Acid Synthase
Epigenetic Reader Domain
mTOR
Beta-Secretase
MAPK
Free radical scavengers
IκB/IKK
ATM/ATR
ribosome
AMPK
Phospholipase
Potassium Channel
DNA Methyltransferase
Ras
NOD-like Receptor (NLR)
CFTR
p53
GPCR
ATPase
Carbonic Anhydrase
Dopamine Receptor
ROR
DNA-PK
Src
Dynamin
LPL Receptor
Reductase
gp120/CD4
Glutathione Peroxidase
Phosphatase
PKA
Photosensitizer
ATG
Nucleoside Antimetabolite/Analog
Glutaminase
Adrenergic Receptor
MAO
Topoisomerase
UGT
PAFR
NMDAR
Glucosidase
Molecular Glues
Opioid Receptor
FAAH
Angiotensin-converting Enzyme (ACE)
Somatostatin
Aurora Kinase
cAMP
IGF-1R
CaMK
DNA
EGFR
OXPHOS
TLR
STING
Aminopeptidase
GPCR19
AIM2
ALK
Neprilysin
PI4K
Complement System
Platelet aggregation
Sodium Channel
S6 Kinase
Protease-activated Receptor
FAK
S1P Receptor
Vitamin
BTK