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Anti-MFN1 Polyclonal Antibody
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Catalog No. TMAB-01131
Alias Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog
Anti-MFN1 Polyclonal Antibody is a Rabbit antibody targeting MFN1. Anti-MFN1 Polyclonal Antibody can be used in FCM.
Anti-MFN1 Polyclonal Antibody
Anti-MFN1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01131Alias Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog
Anti-MFN1 Polyclonal Antibody is a Rabbit antibody targeting MFN1. Anti-MFN1 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MFN1 Polyclonal Antibody is a Rabbit antibody targeting MFN1. Anti-MFN1 Polyclonal Antibody can be used in FCM. |
| Alias | Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Horse,Rabbit) |
| Verified Activity | Blank control: RSC96 (blue), the cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice. Isotype Control Antibody: Rabbit Igg (orange); Secondary Antibody: Goat anti-rabbit IgG-Pe (white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA; Primary Antibody Dilution: 1 μg in 100 μL 1X PBS containing 0.5% BSA (green). |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm and Mitochondrion outer membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2) are homologs for the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins and are mediators of mitochondrial fusion. A GTPase domain is required for Mfn protein function but the molecular mechanisms of the GTPase-dependent reaction as well as the functional division of the two Mfn proteins are unknown. They are essential for embryonic development and may play a role in the pathobiology of obesity. Although the Mfn1 and Mfn2 genes are broadly expressed, they show different levels of expression in different tissues. Two Mfn1 transcripts are elevated in heart, while Mfn2 mRNA is abundantly expressed in heart and muscle tissue but present only at low levels in many other tissues. Mfn1 localizes to mitochondria and participates in at least two different high molecular weight protein complexes in a GTP-dependent manner. Purified recombinant Mfn1 exhibited approximately eightfold higher GTPase activity than Mfn2. |
| Immunogen | KLH conjugated synthetic peptide: human Mfn 1 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Mitochondrial markers,Mitophagy fission and fusion,Parkinson's disease,GTP,Mitochondria |
| Molecular Weight | Theoretical: 81 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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