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LILRA4/CD85g Protein, Cynomolgus, Recombinant (His)
(Synonyms: MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g) Copy Product InfoSynonyms: MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g
Catalog No. TMPK-01301 Copy Product Info
LILRA4/CD85g Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.7 kDa and the accession number is XP_005590346.1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $51 | 7-10 days | 7-10 days | |
| 10 µg | $80 | 7-10 days | 7-10 days | |
| 20 µg | $129 | 7-10 days | 7-10 days | |
| 50 µg | $248 | 7-10 days | 7-10 days | |
| 100 µg | $418 | 7-10 days | 7-10 days | |
| 200 µg | $757 | 7-10 days | 7-10 days | |
| 500 µg | $1,670 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | LILRA4/CD85g Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.7 kDa and the accession number is XP_005590346.1. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | XP_005590346.1 |
| Construction | Glu24-Asn446 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g |
| Research Background | LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. |
| Molecular Weight | 47.7 kDa (predicted). Due to glycosylation, the protein migrates to 58-68 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: LILRA4/CD85g Protein, Cynomolgus, Recombinant (His) chemical structure | LILRA4/CD85g Protein, Cynomolgus, Recombinant (His) molecular weight
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