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Anti-Cathepsin S Antibody (9S226) (Synonyms: Cats, cathepsin S, Cat S)
Catalog No. TMAY-03454 Copy Product Info
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Anti-Cathepsin S Antibody (9S226) is a Rabbit antibody targeting Cathepsin S. Anti-Cathepsin S Antibody (9S226) can be used in ELISA.
Anti-Cathepsin S Antibody (9S226)
Copy Product Info🥰Excellent
Catalog No. TMAY-03454
Synonyms Cats, cathepsin S, Cat S
Anti-Cathepsin S Antibody (9S226) is a Rabbit antibody targeting Cathepsin S. Anti-Cathepsin S Antibody (9S226) can be used in ELISA.
Anti-Cathepsin S Antibody
(9S226)
(9S226)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Cathepsin S Antibody (9S226) is a Rabbit antibody targeting Cathepsin S. Anti-Cathepsin S Antibody (9S226) can be used in ELISA. |
| Synonyms | Cats, cathepsin S, Cat S |
| Ig Type | Rabbit IgG |
| Clone | 9S226 |
| Reactivity | Mouse |
| Specificity | Mouse Cathepsin S No cross-reactivity in ELISA with Human CTSS Mouse CTSA Mouse CTSB Mouse CTSC Mouse CTSD Mouse CTSE Mouse CTSX |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Cathepsin S / CTSS (TMPY-02751; AAB94925.1; Met1-Ile340). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTSS is synthesized as inactive precursor of 331 amino acids consisting of a 15-aa signal peptide, a propeptide of 99 aa, and a mature polypeptide of 217 aa. It is activated in the lysosomes by a proteolytic cleavage of the propeptide. Cathepsin S is expressed in the lysosome of antigen presenting cells, primarily dendritic cells, B-cells and macrophages. Compared with other lysosomal cysteine proteases, cathepsin S has displayed some unique characteristics. Cathepsin S is most well known for its critical function in the proteolytic digestion of the invariant chain chaperone molecules, thus controlling antigen presentation to CD4+ T-cells by major histocompatibility complex (MHC) class II molecules or to NK1.1+ T-cells via CD1 molecules. Cathepsin S also appears to participate in direct processing of exogenous antigens for presentation by MHC class II to CD4+ T-cells, or in cross-presentation by MHC class I molecules to CD8+ T-cells. In addition, although direct evidence is still lacking, in its secreted form cathepsin S is implicated in degradation of the extracellular matrix, which may contribute to the pathology of a number of diseases, including arthritis, atherosclerosis, neurological diseases and chronic obstructive pulmonary disease. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse Cathepsin S / CTSS protein (TMPY-02751) |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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