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Anti-CD81 Antibody-PE (8P60) is a PE-conjugated Mouse antibody targeting CD81. Anti-CD81 Antibody-PE (8P60) can be used in FCM.
Description | Anti-CD81 Antibody-PE (8P60) is a PE-conjugated Mouse antibody targeting CD81. Anti-CD81 Antibody-PE (8P60) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG2b |
Clone | 8P60 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human CD81 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD81. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD81 / TAPA-1 (rh CD81 / TAPA-1; TMPY-03890; NP_004347.1; Phe113-Lys201) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition. |
Conjucates | PE |
Others Formats | Unconjugated/APC/PerCP/FITC/HRP |
Antibody Types Available | 6 |
Immunogen | Recombinant Human CD81 / TAPA-1 Protein (TMPY-03890) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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