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2-O-α-D-Glucopyranosyl-L-ascorbic Acid

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Catalog No. T8172Cas No. 129499-78-1
Alias ASCORBYL GLUCOSIDE

2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, exhibits anti-cancer properties upon enzymatic conversion to ascorbic acid.

2-O-α-D-Glucopyranosyl-L-ascorbic Acid

2-O-α-D-Glucopyranosyl-L-ascorbic Acid

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Purity: 99.73%
Catalog No. T8172Alias ASCORBYL GLUCOSIDECas No. 129499-78-1
2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, exhibits anti-cancer properties upon enzymatic conversion to ascorbic acid.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$34In StockIn Stock
100 mg$44In StockIn Stock
500 mg$106In StockIn Stock
1 g$157In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.73%
Appearance:Solid
Color:White
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Product Introduction

2-O-α-D-Glucopyranosyl-L-ascorbic Acid AI Summary
2-O-α-D-Glucopyranosyl-L-ascorbic Acid exhibits significant antioxidant activity by scavenging hydroxy radicals and reducing inorganic phosphate levels using alpha-glycerophosphate as a substrate, as well as reducing hydroxy radical and acetaldehyde levels when using ethylene glycol as a substrate. The compound also demonstrates potent antioxidant properties by scavenging DPPH free radicals, with activity levels ranging from 1.5 to 2.7 moles of radicals scavenged per mol of antioxidant. Additionally, it was observed to consume 190.0 uM of radicals and form AA-2G-DPPH adducts at 200 uM concentration, with a retention time of 15.0 minutes for the AA-2G-DPPH product. Furthermore, 2-O-α-D-Glucopyranosyl-L-ascorbic Acid exhibits antiviral activity against Herpes simplex virus type 1 in human RD cells by inhibiting virus-induced cytopathic effects, indicating potential specificity towards the virus based on the selectivity ratio of maximum non-toxic concentration for human RD cells to the effective concentration for HSV1..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, exhibits anti-cancer properties upon enzymatic conversion to ascorbic acid.
SynonymsASCORBYL GLUCOSIDE
Chemical Properties
Molecular Weight338.26
FormulaC12H18O11
Cas No.129499-78-1
SmilesOC[C@H](O)[C@H]1OC(=O)C(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=C1O
Relative Density.1.83 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 33 mg/mL (97.56 mM), Sonication is recommended.
DMSO: 33 mg/mL (97.56 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.9563 mL14.7815 mL29.5631 mL147.8153 mL
5 mM0.5913 mL2.9563 mL5.9126 mL29.5631 mL
10 mM0.2956 mL1.4782 mL2.9563 mL14.7815 mL
20 mM0.1478 mL0.7391 mL1.4782 mL7.3908 mL
50 mM0.0591 mL0.2956 mL0.5913 mL2.9563 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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