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Anti-Osteoactivin/GPNMB Antibody (6H8) is an antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (6H8) can be used in ELISA, FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Anti-Osteoactivin/GPNMB Antibody (6H8) is an antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (6H8) can be used in ELISA, FCM. |
Synonyms | Osteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb |
Ig Type | Mouse IgG2a |
Clone | 6H8 |
Reactivity | Human |
Verified Activity | Overlay Peak curve showing Hela cells stained with TMAH-00506 (red line) at 1:100. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 003 events was performed. |
Application | |
Recommended Dose | FCM:1:20-1:500. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Melanosome membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. |
Tissue Specificity | Widely expressed, but very low expression, if any, in the brain. Expressed in the epidermis with higher levels in melanocytes compared with keratinocytes and Langerhans cells (at protein level). Expressed in peripheral blood, but not bone marrow mononucle |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Could be a melanogenic enzyme. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human GPNMB Protein |
Antigen Species | Human |
Gene Name | GPNMB |
Gene ID | |
Uniprot ID | |
Biology Area | Cancer, Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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