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VDAC1 Mitochondrial Loading Control Antibody (5D173)
(Synonyms: YNL2441C, YNL055C, Voltage-dependent anion-selective channel protein 1, Voltage dependent anion selective channel protein 1, Voltage dependent anion channel 1, VDAC-1, VDAC, Porin 31HM, Porin 31HL, POR1, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1, OMP2, N2441, Mitochondrial Porin, MGC111064, hVDAC1) Copy Product Info
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Synonyms: YNL2441C, YNL055C, Voltage-dependent anion-selective channel protein 1, Voltage dependent anion selective channel protein 1, Voltage dependent anion channel 1, VDAC-1, VDAC, Porin 31HM, Porin 31HL, POR1, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1, OMP2, N2441, Mitochondrial Porin, MGC111064, hVDAC1
Catalog No. TMAB-01943 Copy Product Info
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VDAC1 Mitochondrial Loading Control Antibody (5D173) is a Rabbit antibody targeting VDAC1. VDAC1 Mitochondrial Loading Control Antibody (5D173) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
VDAC1 Mitochondrial Loading Control Antibody
(5D173)
(5D173)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $154 | 7-10 days | 7-10 days | |
| 50 μL | $272 | 7-10 days | 7-10 days | |
| 100 μL | $487 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
Color:Transparent
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| Description | VDAC1 Mitochondrial Loading Control Antibody (5D173) is a Rabbit antibody targeting VDAC1. VDAC1 Mitochondrial Loading Control Antibody (5D173) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | YNL2441C, YNL055C, Voltage-dependent anion-selective channel protein 1, Voltage dependent anion selective channel protein 1, Voltage dependent anion channel 1, VDAC-1, VDAC, Porin 31HM, Porin 31HL, POR1, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1, OMP2, N2441, Mitochondrial Porin, MGC111064, hVDAC1 |
| Ig Type | IgG |
| Clone | 5D173 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Endosome membrane; Peripheral membrane protein (Probable). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle. |
| Immunogen | A synthesized peptide: human VDAC1 |
| Antigen Species | Human |
| Gene Name | VDAC1 |
| Gene ID | |
| Protein Name | Voltage-dependent anion-selective channel protein 1 |
| Biology Area | Cellular metabolic process,Metabolism,Mitochondrial,Mitochondrial,VDAC1 - Mitochondrial Preps,Energy Metabolism,Apoptosis,Mitochondrial markers,Cancer,Energy Metabolism,Mitochondrial,Channels,Mitochondria |
| Function | Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. |
| Molecular Weight | Theoretical: 32 kDa. Actual: 32 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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