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Pim-1 kinase inhibitor 8

Name: Pim-1 kinase inhibitor 8
Brand: TargetMol
SKU: T83627
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T83627Cas No. 916038-47-6

Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound for breast cancer research.

Pim-1 kinase inhibitor 8

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Purity: 99.81%

Catalog No. T83627Cas No. 916038-47-6

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$34	In Stock	In Stock
5 mg	$83	In Stock	In Stock
10 mg	$133	In Stock	In Stock
25 mg	$268	In Stock	In Stock
50 mg	$431	In Stock	In Stock
100 mg	$678	In Stock	In Stock
200 mg	$919	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.81%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	275.3
Formula	C₁₄H₁₇N₃O₃
Cas No.	916038-47-6
Smiles	N#CC1=C(N=C(C=C1C)C)OCC(=O)N2CCOCC2
Relative Density.	1.25 g/cm3 at 20℃ (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (290.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6324 mL	18.1620 mL	36.3240 mL	181.6201 mL
5 mM	0.7265 mL	3.6324 mL	7.2648 mL	36.3240 mL
10 mM	0.3632 mL	1.8162 mL	3.6324 mL	18.1620 mL
20 mM	0.1816 mL	0.9081 mL	1.8162 mL	9.0810 mL
50 mM	0.0726 mL	0.3632 mL	0.7265 mL	3.6324 mL
100 mM	0.0363 mL	0.1816 mL	0.3632 mL	1.8162 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc