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Pim-1 kinase inhibitor 8

Name: Pim-1 kinase inhibitor 8
Brand: TargetMol
SKU: T83627
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T83627Cas No. 916038-47-6

Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound for breast cancer research.

Pim-1 kinase inhibitor 8

🥰Excellent

Purity: 99.81%

Catalog No. T83627Cas No. 916038-47-6

Pack Size	Price	Availability
1 mg	$34	In Stock
5 mg	$83	In Stock
10 mg	$133	In Stock
25 mg	$268	In Stock
50 mg	$431	In Stock
100 mg	$678	In Stock
200 mg	$919	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.81%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	275.3
Formula	C₁₄H₁₇N₃O₃
Cas No.	916038-47-6
Smiles	N#CC1=C(N=C(C=C1C)C)OCC(=O)N2CCOCC2
Relative Density.	1.25 g/cm3 at 20℃ (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (290.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6324 mL	18.1620 mL	36.3240 mL	181.6201 mL
5 mM	0.7265 mL	3.6324 mL	7.2648 mL	36.3240 mL
10 mM	0.3632 mL	1.8162 mL	3.6324 mL	18.1620 mL
20 mM	0.1816 mL	0.9081 mL	1.8162 mL	9.0810 mL
50 mM	0.0726 mL	0.3632 mL	0.7265 mL	3.6324 mL
100 mM	0.0363 mL	0.1816 mL	0.3632 mL	1.8162 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc