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Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody
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Catalog No. TMAC-02308
Alias p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74)
Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KRT8 (Ser74). Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody
Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody
😃Good
Catalog No. TMAC-02308Alias p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74)
Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KRT8 (Ser74). Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody can be used in IF,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KRT8 (Ser74). Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody can be used in IF,WB. |
| Synonyms | p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from HepG2 cells untreated or treated with EGF using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. 2. Immunofluorescence staining of methanol-fixed Hela cells using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. 3. Western blot analysis of extracts from 293 cells, treated with calf intestinal phosphatase (CIP), using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308.    |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8) |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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