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Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody
(Synonyms: p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74)) Copy Product Info
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Synonyms: p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74)
Catalog No. TMAC-02308 Copy Product Info
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Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KRT8 (Ser74). Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-KRT8
(Ser74) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $217 | 7-10 days | 7-10 days | |
| 100 µL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KRT8 (Ser74). Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody can be used in IF,WB. |
| Synonyms | p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from HepG2 cells untreated or treated with EGF using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. 2. Immunofluorescence staining of methanol-fixed Hela cells using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. 3. Western blot analysis of extracts from 293 cells, treated with calf intestinal phosphatase (CIP), using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308.  , , |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8) |
| Antigen Species | Human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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