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Triptorelin ([DTrp6]-LH-RH)

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Catalog No. T36371Cas No. 57773-63-4

Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation

Triptorelin ([DTrp6]-LH-RH)

Triptorelin ([DTrp6]-LH-RH)

😃Good
Catalog No. T36371Cas No. 57773-63-4
Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation
Pack SizePriceAvailabilityQuantity
1 mg$38Backorder
5 mg$56Backorder
10 mg$75Backorder
25 mg$98Backorder
50 mg$126Backorder
100 mg$162Backorder
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Product Introduction

Bioactivity
Description
Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation
In vivo
(1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
Chemical Properties
Molecular Weight1311.45
FormulaC64H82N18O13
Cas No.57773-63-4
Relative Density.1.52 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 10 mg/mL (7.63 mM), Sonication is recommended.
PBS (pH 7.2): 3 mg/mL (2.29 mM), Sonication is recommended.
DMSO: 3 mg/mL (2.29 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMSO/DMF
1mg5mg10mg50mg
1 mM0.7625 mL3.8126 mL7.6251 mL38.1257 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

Triptorelin ([DTrp-6]-LH-RH)Triptorelin ([DTrp6]LHRH)Triptorelin ([DTrp6] LH RH)
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