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Triptorelin ([DTrp6]-LH-RH)

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Catalog No. T36371Cas No. 57773-63-4

Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation

Triptorelin ([DTrp6]-LH-RH)

Triptorelin ([DTrp6]-LH-RH)

😃Good
Catalog No. T36371Cas No. 57773-63-4
Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation
Pack SizePriceAvailabilityQuantity
1 mg$38 Backorder
5 mg$56 Backorder
10 mg$75 Backorder
25 mg$98 Backorder
50 mg$126 Backorder
100 mg$162 Backorder
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Product Introduction

Bioactivity
Description
Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
[1]. Wei S et al. Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):197-204.
In vivo
(1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
Chemical Properties
Molecular Weight1311.45
FormulaC64H82N18O13
Cas No.57773-63-4
Relative Density.1.52 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 10 mg/mL (7.63 mM), Sonication is recommended.
PBS (pH 7.2): 3 mg/mL (2.29 mM), Sonication is recommended.
DMSO: 3 mg/mL (2.29 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMSO/DMF
1mg5mg10mg50mg
1 mM0.7625 mL3.8126 mL7.6251 mL38.1257 mL

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Keywords

Triptorelin ([DTrp-6]-LH-RH)Triptorelin ([DTrp6]LHRH)Triptorelin ([DTrp6] LH RH)
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