KLRG1 Protein, Human, Recombinant (hFc)

Catalog No. TMPK-01140

KLRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is Q96E93-1.

KLRG1 Protein, Human, Recombinant (hFc)

Catalog No. TMPK-01140

KLRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is Q96E93-1.

Pack Size	Price	Availability
5 μg	$56	7-10 days
10 μg	$88	7-10 days
20 μg	$143	7-10 days
50 μg	$278	7-10 days
100 μg	$465	7-10 days
200 μg	$839	7-10 days
500 μg	$1,850	7-10 days

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Product Information

Biological Activity	Immobilized Human KLRG1, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-KLRG1 Antibody, hFc Tag with the EC50 of 20.8ng/ml determined by ELISA.
Description	KLRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is Q96E93-1.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	Q96E93-1
Synonyms	MGC13600,MAFAL,MAFA,KLRG1,CLEC15AMAFA-LIKE,CLEC15A,2F1
Construction	Leu60-Phe195
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	42.8 kDa (predicted). Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expressed by a subpopulation of Treg cells with GATA3 effector phenotype.Lack of KLRG1 on Treg cells conferred on them a competitive advantage in the gut, but not in lymphoid organs. Hence, although absence of KLRG1 is not enough to increase intestinal Treg cells in KLRG1 knockout mice, KLRG1 ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.