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Anti-EpCAM/TROP1 Antibody-APC (9H261)
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Catalog No. TMAY-01076A
Alias TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5
Anti-EpCAM/TROP1 Antibody-APC (9H261) is a APC-conjugated Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody-APC (9H261) can be used in FCM.
Anti-EpCAM/TROP1 Antibody-APC (9H261)
Anti-EpCAM/TROP1 Antibody-APC (9H261)
😃Good
Catalog No. TMAY-01076AAlias TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5
Anti-EpCAM/TROP1 Antibody-APC (9H261) is a APC-conjugated Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody-APC (9H261) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $105 | 7-10 days | |
| 100 T | $329 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Human |
| Alias | TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5 |
| Ig Type | Rabbit IgG |
| Clone | 9H261 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of anti-EpCAM (CD326) reactivity on SKBR3 cells. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human EpCAM / TROP1 / CD326 (rh EpCAM / TROP1 / CD326; TMPY-01300; NP_002345.1; Met 1-Lys 265) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/Biotin/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Protein: Human EpCAM / TROP1 / CD326 protein (TMPY-01300) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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