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Anti-Fibrillin-1 Polyclonal Antibody
(Synonyms: Fibrillin-1, FBN1, FBN, Asprosin) Copy Product Info
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Synonyms: Fibrillin-1, FBN1, FBN, Asprosin
Catalog No. TMAB-00155 Copy Product Info
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Anti-Fibrillin-1 Polyclonal Antibody is a Rabbit antibody targeting Fibrillin-1. Anti-Fibrillin-1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Fibrillin-1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Fibrillin-1 Polyclonal Antibody is a Rabbit antibody targeting Fibrillin-1. Anti-Fibrillin-1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | Fibrillin-1, FBN1, FBN, Asprosin |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Detected in endothelial cells (at protein level). Widely expressed. Detected in fetal spleen, lung and brain. Detected in adult liver, muscle, thymus, placenta, lung, testis, ovary, prostate, heart, and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human FBN1 |
| Antigen Species | Human |
| Gene Name | FBN1 |
| Gene ID | |
| Protein Name | Fibrillin-1 |
| Uniprot ID | |
| Biology Area | Extended Fibrils |
| Function | Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. |
| Molecular Weight | Theoretical: 316 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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