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Anti-Phospho-SMAD2 (Ser250) Antibody (7J329)
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Catalog No. TMAH-00963
Alias SMAD2 (p-Ser250), SMAD2 (p-S250), p-SMAD2 (Ser250), p-SMAD2 (S250), Phospho-SMAD2 (S250)
Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) is an antibody targeting Phospho-SMAD2 (Ser250). Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) can be used in ELISA,WB.
Anti-Phospho-SMAD2 (Ser250) Antibody (7J329)
Anti-Phospho-SMAD2 (Ser250) Antibody (7J329)
😃Good
Catalog No. TMAH-00963Alias SMAD2 (p-Ser250), SMAD2 (p-S250), p-SMAD2 (Ser250), p-SMAD2 (S250), Phospho-SMAD2 (S250)
Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) is an antibody targeting Phospho-SMAD2 (Ser250). Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) can be used in ELISA,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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| Description | Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) is an antibody targeting Phospho-SMAD2 (Ser250). Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) can be used in ELISA,WB. |
| Synonyms | SMAD2 (p-Ser250), SMAD2 (p-S250), p-SMAD2 (Ser250), p-SMAD2 (S250), Phospho-SMAD2 (S250) |
| Ig Type | Rabbit IgG |
| Clone | 7J329 |
| Reactivity | Human |
| Verified Activity | Western Blot -Positive WB detected in Hela whole cell lysate,A549 whole cell lysate -All lanes Phospho-SMAD2 antibody at 1.07μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 58 KDa -Observed band size: 58 KDa |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Phospho-SMAD2 (S250) |
| Antigen Species | Human |
| Gene Name | SMAD2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal Transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
SMAD2 (pSer250)SMAD2 (pS250)SMAD2 (phospho-Ser250)SMAD2 (phospho-S250)SMAD2SMAD family member 2 (SMAD 2;Smad2;hSMAD2)SMAD 2pSMAD2 (Ser250)pSMAD2 (S250)Mothers against DPP homolog 2Mothers against decapentaplegic homolog 2Mad-related protein 2 (hMAD-2)MADR2MADR 2MADH2MADH 2MAD homolog2MAD homolog 2JV18-1JV 18-1hMAD-2hMAD2
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