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Anti-Antithrombin III Antibody (1P791) (Synonyms: SerpinC1, serpin peptidase inhibitor, clade C (antithrombin),...)
Catalog No. TMAY-00337 Copy Product Info
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Anti-Antithrombin III Antibody (1P791) is a Rabbit antibody targeting Antithrombin III. Anti-Antithrombin III Antibody (1P791) can be used in ELISA.
Anti-Antithrombin III Antibody (1P791)
Copy Product Info🥰Excellent
Catalog No. TMAY-00337
Synonyms SerpinC1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Anti-Antithrombin III Antibody (1P791) is a Rabbit antibody targeting Antithrombin III. Anti-Antithrombin III Antibody (1P791) can be used in ELISA.
Anti-Antithrombin III Antibody
(1P791)
(1P791)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $270 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Antithrombin III Antibody (1P791) is a Rabbit antibody targeting Antithrombin III. Anti-Antithrombin III Antibody (1P791) can be used in ELISA. |
| Synonyms | SerpinC1, serpin peptidase inhibitor, clade C (antithrombin), member 1 |
| Ig Type | Rabbit IgG |
| Clone | 1P791 |
| Reactivity | Human |
| Specificity | Human Antithrombin III No cross-reactivity in ELISA with Human SerpinA1 Human SerpinA3 Human SerpinA5 Mouse SerpinF2 Human SerpinF1 Human SerpinD1 Mouse SerpinD1 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Antithrombin III / ATIII / SerpinC1 (rh Antithrombin III / ATIII / SerpinC1; TMPY-00916; NP_000479.1; Met 1-Lys 464). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors, and has been found to be a marker for disseminated intravascular coagulation (DIC) and to be of prognostic significance in septic patients. SerpinC1 synthesized in the liver is the principal plasma serpin of blood coagulation proteases and inhibits thrombin and other factors such as Xa by the formation of covalently linked complexes. Thus it is one of the most important coagulation inhibitors and the fundamental enzyme for the therapeutical action of heparin. In common with SerpinA5 and D1, the inhibitory activity of SerpinC1 undergoes a dramatic increase in the presence of heparin and other glycosaminoglycans. ATIII mediates the promotion of prostaglandin release, an inhibitor of leucocyte activation and downregulator of many proinflammatory cytokines. Antithrombin III exerts anti-inflammatory properties in addition to its anti-coagulative mechanisms. In animal models of sepsis, ATIII affected cytokine plasma concentrations with a decrease of pro-inflammatory cytokines. The deficiency or functional abnormality of ATIII may result in an increased risk of thromboembolic disease, such as deep vein thrombosis and pulmonary embolism. In addition, it has been reported that SerpinC1 can alter or influence inflammatory processes via inhibition of NF-κB activation or actin polymerization. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Serpin C1 protein (TMPY-00916) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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