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Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody

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Catalog No. TMAC-02229

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Aconitase 1 (Ser138). Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody can be used in IHC-P,ICC/IF,ELISA.

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody

😃Good
Catalog No. TMAC-02229
Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Aconitase 1 (Ser138). Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody can be used in IHC-P,ICC/IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Aconitase 1 (Ser138). Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody can be used in IHC-P,ICC/IF,ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundaconitase 1(ACO1) Homo sapiens The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human IREB1 around the phosphorylation site of Ser138. AA range:106-155
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 98 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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