Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852)
😃Good
Catalog No. TMAC-03221
Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) is a Rabbit antibody targeting Phospho-GSK3A/B (Y216/Y279). Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) can be used in WB,ICC,IHC,IP.
Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852)
Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852)
😃Good
Catalog No. TMAC-03221
Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) is a Rabbit antibody targeting Phospho-GSK3A/B (Y216/Y279). Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) can be used in WB,ICC,IHC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) is a Rabbit antibody targeting Phospho-GSK3A/B (Y216/Y279). Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) can be used in WB,ICC,IHC,IP. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Glycogen synthase kinase-3α (GSK-3α) and GSK-3β are highly similar isoforms of serine/ threonine kinases that regulate metabolic enzymes and transcription factors, which are responsible for coordinating processes such as glycogen synthesis and cell adhesion. GSK-3β activity is also required for nuclear activity of Rel dimers, which mediate an apoptotic response to TNFα in mice. GSK-3 catalytic kinase activity is controlled through differential phosphorylation of serine/threonine residues, which have an inhibitory effect, and tyrosine residues, which have an activating effect. Growth factor stimulation of mammalian cells expressing GSK-3α and GSK-3β induces phosphorylation of Ser 21 and Ser 9, respectively, through a phosphatidylinositol 3-kinase (PI 3-K)-protein kinase B (PKB)-dependent pathway, thereby enhancing proliferative signals. Additionally, GSK-3 physically associates with cAMP-dependent protein kinase A (PKA), which phosphorylates Ser 21 of GSK-3α or Ser 9 of GSK-3β and inactivates both forms. GSK-3α/β is positively regulated by phosphorylation on Tyr 279 and Tyr 216, respectively. Activated GSK-3α/β participates in energy metabolism, neuronal cell development, and body pattern formation. Tyrosine dephosphorylation of GSK-3 is involved in its extracellular signal-dependent inactivation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human GSK3(alpha+beta) around the phosphorylation site of Tyr216 and 279 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 51 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) | purchase Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) | Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) cost | order Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) | Anti-Phospho-GSK3A/B (Y216/Y279) Antibody (3N852) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.