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Anti-DGAT1 Polyclonal Antibody
(Synonyms: Retinol O fatty acyltransferase, MGC139064, hCG_24006, EC 2.3.1.20, Diglyceride acyltransferase, Diacylglycerol O-acyltransferase 1, DGAT1, Dgat, D15Ertd23e, C75990, ARGP1, ARAT, Acyl-CoA:diacylglycerol acyltransferase, Acyl-CoA retinol O-fatty-acyltransferase, Acyl coenzyme A:cholesterol acyltransferase related gene 1, ACAT-related gene product 1) Copy Product Info
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Synonyms: Retinol O fatty acyltransferase, MGC139064, hCG_24006, EC 2.3.1.20, Diglyceride acyltransferase, Diacylglycerol O-acyltransferase 1, DGAT1, Dgat, D15Ertd23e, C75990, ARGP1, ARAT, Acyl-CoA:diacylglycerol acyltransferase, Acyl-CoA retinol O-fatty-acyltransferase, Acyl coenzyme A:cholesterol acyltransferase related gene 1, ACAT-related gene product 1
Catalog No. TMAB-00542 Copy Product Info
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Anti-DGAT1 Polyclonal Antibody is a Rabbit antibody targeting DGAT1. Anti-DGAT1 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
Anti-DGAT1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-DGAT1 Polyclonal Antibody is a Rabbit antibody targeting DGAT1. Anti-DGAT1 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | Retinol O fatty acyltransferase, MGC139064, hCG_24006, EC 2.3.1.20, Diglyceride acyltransferase, Diacylglycerol O-acyltransferase 1, DGAT1, Dgat, D15Ertd23e, C75990, ARGP1, ARAT, Acyl-CoA:diacylglycerol acyltransferase, Acyl-CoA retinol O-fatty-acyltransferase, Acyl coenzyme A:cholesterol acyltransferase related gene 1, ACAT-related gene product 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed. |
| Immunogen | KLH conjugated synthetic peptide: human DGAT1 |
| Antigen Species | Human |
| Gene Name | DGAT1 |
| Gene ID | |
| Protein Name | Diacylglycerol O-acyltransferase 1 |
| Uniprot ID | |
| Biology Area | Metabolism of lipids and lipoproteins,Metabolism,Fatty acids,Lipid metabolism,Fatty acid oxidation,Lipid metabolism,Lipid Signaling |
| Function | Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. |
| Molecular Weight | Theoretical: 55 kDa. Actual: 60 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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