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Anti-TBR2 Polyclonal Antibody
(Synonyms: T-brain-2, Tbr 2, T-box brain protein 2, t box brain 2, Eomesodermin homolog, Eomesodermin, EOMES) Copy Product Info
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Synonyms: T-brain-2, Tbr 2, T-box brain protein 2, t box brain 2, Eomesodermin homolog, Eomesodermin, EOMES
Catalog No. TMAB-01812 Copy Product Info
🥰Excellent
Anti-TBR2 Polyclonal Antibody is a Rabbit antibody targeting TBR2. Anti-TBR2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P.
Anti-TBR2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TBR2 Polyclonal Antibody is a Rabbit antibody targeting TBR2. Anti-TBR2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P. |
| Synonyms | T-brain-2, Tbr 2, T-box brain protein 2, t box brain 2, Eomesodermin homolog, Eomesodermin, EOMES |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in CD8+ T-cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | EOMES (eomesodermin homolog), also known as TBR2 (T-box-brain2), is the 686 amino acid human homolog of the mouse Eomes protein that contains one T-box DNA binding domain. Genes that contain T-box domains encode proteins that function as transcription factors and are often involved in the regulation of various developmental events. Localized to the nucleus and expressed in the developing brain, EOMES is thought to be involved in neuronal migration and division and may play a role in trophoblast development and gastrulation. Silencing of the EOMES gene can cause mutated or arrested development and may lead to microcephaly disorders which are characterized by reduced head circumference and a malformed brain. |
| Immunogen | KLH conjugated synthetic peptide: human TBR2 |
| Antigen Species | Human |
| Gene Name | EOMES |
| Gene ID | |
| Protein Name | Eomesodermin homolog |
| Uniprot ID | |
| Biology Area | Trophectoderm,Germ cell markers,Soma marker,Neural Signal Transduction,Neurogenesis,Embryonic Germ Cells,Intracellular |
| Function | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. |
| Molecular Weight | Theoretical: 73 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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