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Anti-PD-L1 Antibody (2Z518)

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Catalog No. TMAB-01363

Anti-PD-L1 Antibody (2Z518) is a Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody (2Z518) can be used in WB.

Anti-PD-L1 Antibody (2Z518)

Anti-PD-L1 Antibody (2Z518)

😃Good
Catalog No. TMAB-01363
Anti-PD-L1 Antibody (2Z518) is a Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody (2Z518) can be used in WB.
Pack SizePriceAvailabilityQuantity
25 μL$155 7-10 days
50 μL$271 7-10 days
100 μL$488 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: WB

Reactivity: Human
Ig Type
IgG
Clone
2Z518
Reactivity
Human
Verified Activity
25 μg total protein per Lane of various lysates probed with PD-L1 monoclonal antibody, unconjugated (TMAB-01363) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
Application
WB
Recommended Dose
WB: 1:200-1000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PD-L1
Antigen Species
Human
Gene ID
29126
Uniprot ID
Biology Area
Tumor antigens,Tumor-associated antigens,Non-lineage,Autoimmune,pd-l1
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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