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Anti-PD-L1 Antibody (2Z518) is a Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody (2Z518) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μL | $155 | 7-10 days | |
50 μL | $271 | 7-10 days | |
100 μL | $488 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: WB Reactivity: Human |
Ig Type | IgG |
Clone | 2Z518 |
Reactivity | Human |
Verified Activity | 25 μg total protein per Lane of various lysates probed with PD-L1 monoclonal antibody, unconjugated (TMAB-01363) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
Application | WB |
Recommended Dose | WB: 1:200-1000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein. |
Construction | Recombinant Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Immunogen | KLH conjugated synthetic peptide: human PD-L1 |
Antigen Species | Human |
Gene ID | 29126 |
Uniprot ID | |
Biology Area | Tumor antigens,Tumor-associated antigens,Non-lineage,Autoimmune,pd-l1 |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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