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Anti-TLR2 Antibody (5A444) (Synonyms: toll-like receptor 2)
Catalog No. TMAY-00202 Copy Product Info
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Anti-TLR2 Antibody (5A444) is a Mouse antibody targeting TLR2. Anti-TLR2 Antibody (5A444) can be used in IHC-P.
Anti-TLR2 Antibody (5A444)
Copy Product Info🥰Excellent
Catalog No. TMAY-00202
Synonyms toll-like receptor 2
Anti-TLR2 Antibody (5A444) is a Mouse antibody targeting TLR2. Anti-TLR2 Antibody (5A444) can be used in IHC-P.
Anti-TLR2 Antibody
(5A444)
(5A444)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Related Conjugates and Formulations
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| Description | Anti-TLR2 Antibody (5A444) is a Mouse antibody targeting TLR2. Anti-TLR2 Antibody (5A444) can be used in IHC-P. |
| Synonyms | toll-like receptor 2 |
| Ig Type | Mouse IgG1 |
| Clone | 5A444 |
| Reactivity | Human |
| Specificity | Human TLR2 |
| Verified Activity | Immunochemical staining of human TLR2 in human brain with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TLR2 (CD282) (rh TLR2 (CD282); TMPY-02794; O60603-1; Met1-Arg587). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathogen recognition and activation of innate immunity. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 contains 14 LRR (leucine-rich) repeats and 1 TIR domain. TLR2 gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. CD282 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. It also cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. CD282 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It may also promote apoptosis in response to lipoproteins. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TLR2 (CD282) Protein (TMPY-02794) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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