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Anti-Phospho-CBL (Tyr674) Polyclonal Antibody (Synonyms: RNF55, Proto-oncogene c-Cbl, p-CBL (Y674), p-CBL (Ty...)

Catalog No. TMAC-00629 Copy Product Info
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Anti-Phospho-CBL (Tyr674) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CBL (Tyr674). Anti-Phospho-CBL (Tyr674) Polyclonal Antibody can be used in WB.

Anti-Phospho-CBL (Tyr674) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00629
Synonyms RNF55, Proto-oncogene c-Cbl, p-CBL (Y674), p-CBL (Tyr674), CBL2, CBL (p-Y674), CBL (p-Tyr674)

Anti-Phospho-CBL (Tyr674) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CBL (Tyr674). Anti-Phospho-CBL (Tyr674) Polyclonal Antibody can be used in WB.

Anti-Phospho-CBL
(Tyr674) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-CBL (Tyr674) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CBL (Tyr674). Anti-Phospho-CBL (Tyr674) Polyclonal Antibody can be used in WB.
SynonymsRNF55, Proto-oncogene c-Cbl, p-CBL (Y674), p-CBL (Tyr674), CBL2, CBL (p-Y674), CBL (p-Tyr674)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from HepG2 cells treated with Na2VO3 using Phospho-CBL (Tyr674) antibody TMAC-00629. The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundParticipates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Tyrosine674 (A-I-Y(p)-S-L) derived from Human CBL
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 120 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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