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CP-316819

Name: CP-316819
Brand: TargetMol
SKU: T22683
Rating: 4.5 (1 reviews)

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Catalog No. T22683Cas No. 186392-43-8

Alias GPi 819, CP 316819

CP-316819 (GPi 819) is a potent inhibitor of glycogen phosphorylase (GPase) with hypoglycemic effects, inhibits huSMGPa and huLGPa, maintains neuronal activity during hypoglycemia, and can be used in the study of hyperglycemia.

CP-316819

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Purity: 98.01%

Catalog No. T22683Alias GPi 819, CP 316819Cas No. 186392-43-8

Pack Size	Price	Availability	Quantity
2 mg	$53	5 days

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Batch Information

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Purity:98.01%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CP-316819 (GPi 819) is a potent inhibitor of glycogen phosphorylase (GPase) with hypoglycemic effects, inhibits huSMGPa and huLGPa, maintains neuronal activity during hypoglycemia, and can be used in the study of hyperglycemia.
Synonyms	GPi 819, CP 316819

Chemical Properties

Molecular Weight	415.87
Formula	C₂₁H₂₂ClN₃O₄
Cas No.	186392-43-8
Smiles	CON(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1
Relative Density.	1.357 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Ethanol: <41.59 mg/mL, Sonication is recommended.

DMSO: 100 mg/mL (240.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4046 mL	12.0230 mL	24.0460 mL	120.2299 mL
5 mM	0.4809 mL	2.4046 mL	4.8092 mL	24.0460 mL
10 mM	0.2405 mL	1.2023 mL	2.4046 mL	12.0230 mL
20 mM	0.1202 mL	0.6011 mL	1.2023 mL	6.0115 mL
50 mM	0.0481 mL	0.2405 mL	0.4809 mL	2.4046 mL
100 mM	0.0240 mL	0.1202 mL	0.2405 mL	1.2023 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CP-316819CP316819