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PTK9 Protein, Human, Recombinant (His & GST)

Catalog No. TMPY-01822
Synonyms: PTK9, MGC41876, A6, MGC23788, twinfilin actin binding protein 1

PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.

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PTK9 Protein, Human, Recombinant (His & GST)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
Species Human
Expression System E. coli
Tag His, GST
Accession Number Q12792-4
Synonyms PTK9, MGC41876, A6, MGC23788, twinfilin actin binding protein 1
Construction The Human TWF1 isoform 4 (Q12792-4) (Met 1-Asp 252) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Protein Purity > 84 % as determined by SDS-PAGE
Molecular Weight 57 kDa (predicted)
Endotoxin Please contact us for more information.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 500 mM NaCl, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background Twinfilin-1, also known as Protein A6, Protein tyrosine kinase 9, TWF1 and PTK9, is a cytoplasm protein that belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the mammalian twinfilin-1, a second protein with approximately 65% sequence identity to twinfilin-1 exists in mouse and humans. TWF1 / PTK9 is expressed at high levels in the colon, testis, ovary, prostate and lung. It is expressed at lower levels in the brain, bladder and heart. It is not detected in liver. TWF1 / PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. TWF1 / PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.

References and Literature

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Keywords

PTK9 Protein, Human, Recombinant (His & GST) PTK9 MGC-41876 MGC 23788 A-6 MGC41876 PTK-9 A6 MGC-23788 PTK 9 MGC23788 A 6 MGC 41876 twinfilin actin binding protein 1 recombinant recombinant-proteins proteins protein

 

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