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m-PEG5-acid

Name: m-PEG5-acid
Brand: TargetMol
SKU: T15888
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15888Cas No. 81836-43-3

m-PEG5-acid is a PEG-based linker for PROTACs that joins two essential ligands, aiding in the formation of PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

m-PEG5-acid

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Catalog No. T15888Cas No. 81836-43-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Resource Download

COA MS HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	280.31
Formula	C₁₂H₂₄O₇
Cas No.	81836-43-3
Smiles	COCCOCCOCCOCCOCCC(O)=O
Relative Density.	1.107 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (285.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5675 mL	17.8374 mL	35.6748 mL	178.3739 mL
5 mM	0.7135 mL	3.5675 mL	7.1350 mL	35.6748 mL
10 mM	0.3567 mL	1.7837 mL	3.5675 mL	17.8374 mL
20 mM	0.1784 mL	0.8919 mL	1.7837 mL	8.9187 mL
50 mM	0.0713 mL	0.3567 mL	0.7135 mL	3.5675 mL
100 mM	0.0357 mL	0.1784 mL	0.3567 mL	1.7837 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc