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Anti-NOX4 Antibody (4J332)
(Synonyms: RENOX, Renal NAD(P)H-oxidase, NOX4, NADPH oxidase 4, Kidney superoxide-producing NADPH oxidase, Kidney oxidase-1 (KOX-1)) Copy Product Info
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Synonyms: RENOX, Renal NAD(P)H-oxidase, NOX4, NADPH oxidase 4, Kidney superoxide-producing NADPH oxidase, Kidney oxidase-1 (KOX-1)
Catalog No. TMAC-02745 Copy Product Info
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Anti-NOX4 Antibody (4J332) is a Rabbit antibody targeting NOX4. Anti-NOX4 Antibody (4J332) can be used in ICC,IHC,IP,WB.
Anti-NOX4 Antibody
(4J332)
(4J332)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-NOX4 Antibody (4J332) is a Rabbit antibody targeting NOX4. Anti-NOX4 Antibody (4J332) can be used in ICC,IHC,IP,WB. |
| Synonyms | RENOX, Renal NAD(P)H-oxidase, NOX4, NADPH oxidase 4, Kidney superoxide-producing NADPH oxidase, Kidney oxidase-1 (KOX-1) |
| Ig Type | IgG |
| Clone | 4J332 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. Nox4 (also known as Renox) is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of Angiotensin II increases Nox4 expression, which suggests a role for Nox4 in vascular oxidative stress response. The gene encoding human Nox4 maps to chromosome 11q14.2-q21. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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