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Anti-PIGR Antibody (8O945) is a Rabbit antibody targeting PIGR. Anti-PIGR Antibody (8O945) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
Alias | polymeric immunoglobulin receptor, Pigr |
Ig Type | Rabbit IgG |
Clone | 8O945 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 0.1-0.2 μg/mL |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PIGR extracellular domain (rh PIGR; TMPY-00902; NP_002635.2; Met1-Arg638,365Ser/Gly). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human PIGR protein (TMPY-00902) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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