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Ribosomal protein L3 peptide (202-222) amide

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Catalog No. TP2187

Ribosomal protein L3 peptide (202-222) is a peptide with the sequenceH2N-Met-Ser-His-Arg-Lys-Tyr-Glu-Ala-Pro-Arg-His-Gly-His-Leu-Gly-Phe-Leu-Pro-Arg-Lys-Arg-amide, MW=2573.

Ribosomal protein L3 peptide (202-222) amide

Ribosomal protein L3 peptide (202-222) amide

😃Good
Catalog No. TP2187
Ribosomal protein L3 peptide (202-222) is a peptide with the sequenceH2N-Met-Ser-His-Arg-Lys-Tyr-Glu-Ala-Pro-Arg-His-Gly-His-Leu-Gly-Phe-Leu-Pro-Arg-Lys-Arg-amide, MW=2573.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68InquiryInquiry
5 mg$198InquiryInquiry
10 mg$329InquiryInquiry
25 mg$459InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Ribosomal protein L3 peptide (202-222) is a peptide with the sequenceH2N-Met-Ser-His-Arg-Lys-Tyr-Glu-Ala-Pro-Arg-His-Gly-His-Leu-Gly-Phe-Leu-Pro-Arg-Lys-Arg-amide, MW=2573.
In vitro
Ribosomes are the particles that catalyze mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Ribosomal protein L3 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L3 is known to bind to the 23S rRNA and may participate in the formation of the peptidyltransferase center of the ribosome [1][2].
In vivo
This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to Tat-mediated transactivation [3].
Chemical Properties
Molecular Weight2573
FormulaC114H182N42O25S
SmilesN[C@]([H])(CC[S]C)C(=O)N[C@]([H])(CO)C(=O)N[C@]([H])(CC=1NC=NC=1)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCCCN)C(=O)N[C@@]([H])(C/C2=C/C=C(/O)C=C2)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@](C)([H])C(=O)N3CCC[C@@]3([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(C/C4=C/N=CN4)C(=O)NCC(=O)N[C@@]([H])(C/C5=C/N=CN5)C(=O)N[C@@]([H])(CC(C)(C)[H])C(=O)NCC(=O)N[C@@]([H])(C/C6=C/C=CC=C6)C(=O)N[C@@]([H])(CC(C)(C)[H])C(=O)N7CCC[C@]7([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(CCCNC(N)=N)C(N)=O
Relative Density.no data available
SequenceH-D-Met-D-Ser-D-His-D-Arg-D-Lys-Tyr-Glu-D-Ala-Pro-Arg-D-His-Gly-His-Leu-Gly-Phe-Leu-D-Pro-Arg-Lys-D-Arg-NH2
Sequence ShortMSHRKYEAPRHGHLGFLPRKR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: ≥257.3 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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