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Filipin complex

Name: Filipin complex
Brand: TargetMol
SKU: T11287
Price: 49 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11287Cas No. 11078-21-0

Filipin complex is a 28-membered cyclopentene macrolide antifungal antibiotic produced by a mixture of S. filipinensis, S. avermitilis, and S. miharaensis that inhibits the entry of PRRSV viruses into cells.

Filipin complex

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Purity: 98%

Catalog No. T11287Cas No. 11078-21-0

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
2 mg	$49	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98%

Appearance:Solid

Color:White to Yellow

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COA HPLC

Product Introduction

Bioactivity

Description	Filipin complex is a 28-membered cyclopentene macrolide antifungal antibiotic produced by a mixture of S. filipinensis, S. avermitilis, and S. miharaensis that inhibits the entry of PRRSV viruses into cells.
In vitro	Filipin complex (2 μg/mL; 1+48 hours) can inhibit the entry of PRRSV. The genomic copies of PRRSV in infected MARC-145 cells decreased by 61% [2].

Chemical Properties

Molecular Weight	1916.517
Formula	C₁₀₅H₁₇₄O₃₀
Cas No.	11078-21-0
Smiles	CCCCCC[C@@H]1[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@H](O)\C(C)=C\C=C\C=C\C=C\C=C\C[C@@H](C)OC1=O.CCCCCC[C@@H]1[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@H](O)\C(C)=C\C=C\C=C\C=C\C=C\[C@H](O)[C@@H](C)OC1=O.CCCCC[C@@H](O)[C@@H]1[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@H](O)\C(C)=C\C=C\C=C\C=C\C=C\[C@H](O)[C@@H](C)OC1=O \|t:28,30,32,34,36,72,74,76,78,80,118,120,122,124,126\|
Relative Density.	1.161 g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 25.00 mg/mL (13.04 mM), Sonication is recommended.

DMSO: 100.00 mg/mL (52.18 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4.00 mg/mL (2.09 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	0.5218 mL	2.6089 mL	5.2178 mL	26.0890 mL
5 mM	0.1044 mL	0.5218 mL	1.0436 mL	5.2178 mL
10 mM	0.0522 mL	0.2609 mL	0.5218 mL	2.6089 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.0261 mL	0.1304 mL	0.2609 mL	1.3044 mL
50 mM	0.0104 mL	0.0522 mL	0.1044 mL	0.5218 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc