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Kaempferol 5,7,4'-trimethyl ether

🥰Excellent
Catalog No. TN4371Cas No. 1098-92-6
Alias 3-Hydroxy-5,7,4′-trimethoxyflavone

Kaempferol 5,7,4'-trimethyl ether inhibits the NF-κB p65 subunit in HeLa cells, inhibits the growth of HT-29 cells and CCD-112CoN cells, and inhibits LPS-induced NO production in RAW 264.7 cells, making it useful for colon cancer research.

Kaempferol 5,7,4'-trimethyl ether

Kaempferol 5,7,4'-trimethyl ether

🥰Excellent
Catalog No. TN4371Alias 3-Hydroxy-5,7,4′-trimethoxyflavoneCas No. 1098-92-6
Kaempferol 5,7,4'-trimethyl ether inhibits the NF-κB p65 subunit in HeLa cells, inhibits the growth of HT-29 cells and CCD-112CoN cells, and inhibits LPS-induced NO production in RAW 264.7 cells, making it useful for colon cancer research.
Pack SizePriceAvailabilityQuantity
1 mg$123In Stock
5 mg$297In Stock
10 mg$463In Stock
25 mg$883In Stock
50 mg$1,320In Stock
100 mg$1,980In Stock
1 mL x 10 mM (in DMSO)$223In Stock
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Product Introduction

Bioactivity
Description
Kaempferol 5,7,4'-trimethyl ether inhibits the NF-κB p65 subunit in HeLa cells, inhibits the growth of HT-29 cells and CCD-112CoN cells, and inhibits LPS-induced NO production in RAW 264.7 cells, making it useful for colon cancer research.
Synonyms3-Hydroxy-5,7,4′-trimethoxyflavone
Chemical Properties
Molecular Weight328.32
FormulaC18H16O6
Cas No.1098-92-6
SmilesO=C1C(O)=C(OC2=CC(OC)=CC(OC)=C12)C=3C=CC(OC)=CC3
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (243.66 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0458 mL15.2290 mL30.4581 mL152.2904 mL
5 mM0.6092 mL3.0458 mL6.0916 mL30.4581 mL
10 mM0.3046 mL1.5229 mL3.0458 mL15.2290 mL
20 mM0.1523 mL0.7615 mL1.5229 mL7.6145 mL
50 mM0.0609 mL0.3046 mL0.6092 mL3.0458 mL
100 mM0.0305 mL0.1523 mL0.3046 mL1.5229 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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