Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JZP-MA-11 is a positron emission tomography (PET) ligand that specifically targets the endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. It exhibits selective inhibition of ABHD6, achieving an IC50 value of 126 nM and is capable of crossing the blood-brain barrier (BBB). The compound, labeled with [18F], demonstrates promising potential for preclinical evaluation in both mice and nonhuman primates (NHP) as a tool for investigating brain ABHD6 activity [1].
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50 mg | Inquiry | Inquiry |
Description | JZP-MA-11 is a positron emission tomography (PET) ligand that specifically targets the endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. It exhibits selective inhibition of ABHD6, achieving an IC50 value of 126 nM and is capable of crossing the blood-brain barrier (BBB). The compound, labeled with [18F], demonstrates promising potential for preclinical evaluation in both mice and nonhuman primates (NHP) as a tool for investigating brain ABHD6 activity [1]. |
Molecular Weight | 336.38 |
Formula | C15H17FN4O2S |
CAS No. | 1672691-50-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JZP-MA-11 1672691-50-7 inhibitor inhibit