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Anti-NAALADL1 Antibody (3U769)
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Catalog No. TMAY-03495
Alias N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964
Anti-NAALADL1 Antibody (3U769) is a Rabbit antibody targeting NAALADL1. Anti-NAALADL1 Antibody (3U769) can be used in IHC-P.
Anti-NAALADL1 Antibody (3U769)
Anti-NAALADL1 Antibody (3U769)
😃Good
Catalog No. TMAY-03495Alias N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964
Anti-NAALADL1 Antibody (3U769) is a Rabbit antibody targeting NAALADL1. Anti-NAALADL1 Antibody (3U769) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $292 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Mouse |
| Alias | N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964 |
| Ig Type | Rabbit IgG |
| Clone | 3U769 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse NAALADL1 in mouse spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse NAALADL1 in mouse small intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse NAALADL1 (rM NAALADL1; TMPY-02668; Q7M758; Pro29-Leu745). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse NAALADL1 protein (TMPY-02668) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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