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β-D-glucuronide-pNP-carbonate

Name: β-D-glucuronide-pNP-carbonate
Brand: TargetMol
SKU: T41022
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T41022Cas No. 894095-98-8

Alias beta-D-glucuronide-pNP-carbonat

β-D-glucuronide-pNP-carbonate (beta-D-glucuronide-pNP-carbonat) is a degradable ADC linker, used in the synthesis of ADC compounds.

β-D-glucuronide-pNP-carbonate

🥰Excellent

Purity: 99.78%

Catalog No. T41022Alias beta-D-glucuronide-pNP-carbonatCas No. 894095-98-8

β-D-glucuronide-pNP-carbonate (beta-D-glucuronide-pNP-carbonat) is a degradable ADC linker, used in the synthesis of ADC compounds.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$39	-	In Stock
10 mg	$55	-	In Stock
25 mg	$89	-	In Stock
50 mg	$129	-	In Stock
100 mg	$228	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

Batch Information

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Purity:99.78%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	β-D-glucuronide-pNP-carbonate (beta-D-glucuronide-pNP-carbonat) is a degradable ADC linker, used in the synthesis of ADC compounds.
Synonyms	beta-D-glucuronide-pNP-carbonat

Chemical Properties

Molecular Weight	913.83
Formula	C₄₅H₄₃N₃O₁₈
Cas No.	894095-98-8
Smiles	C(OC(NCCC(NC1=C(O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](C(OC)=O)O2)C=CC(COC(OC3=CC=C(N(=O)=O)C=C3)=O)=C1)=O)=O)C4C=5C(C=6C4=CC=CC6)=CC=CC5

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100.00 mg/mL (109.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0943 mL	5.4715 mL	10.9430 mL	54.7148 mL
5 mM	0.2189 mL	1.0943 mL	2.1886 mL	10.9430 mL
10 mM	0.1094 mL	0.5471 mL	1.0943 mL	5.4715 mL
20 mM	0.0547 mL	0.2736 mL	0.5471 mL	2.7357 mL
50 mM	0.0219 mL	0.1094 mL	0.2189 mL	1.0943 mL
100 mM	0.0109 mL	0.0547 mL	0.1094 mL	0.5471 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc