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Anti-LAMP3/CD208 Antibody (2F47)
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Catalog No. TMAY-00945
Alias lysosomal associated membrane protein 3, LAMP3
Anti-LAMP3/CD208 Antibody (2F47) is a Mouse antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2F47) can be used in ELISA.
Anti-LAMP3/CD208 Antibody (2F47)
Anti-LAMP3/CD208 Antibody (2F47)
😃Good
Catalog No. TMAY-00945Alias lysosomal associated membrane protein 3, LAMP3
Anti-LAMP3/CD208 Antibody (2F47) is a Mouse antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2F47) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | 189 € | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-LAMP3/CD208 Antibody (2F47) is a Mouse antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2F47) can be used in ELISA. |
| Alias | lysosomal associated membrane protein 3, LAMP3 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2F47 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD208 / LAMP3 (rh LAMP3; TMPY-01013; NP_055213.2; Lys 28-Thr 381). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human LAMP3 protein (TMPY-01013) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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